Friday, July 15, 2005

Thickness of ventromedial prefrontal cortex in humans is correlated with extinction memory

Article published online in PNAS.

The ventromedial prefrontal cortex is a part of the brain which has been show to be involved in fear extinction. In this study, the subjects were conditioned to associate a light with an electric shock. Then they were shown the light without the shock - the extinction phase. The next day they were again shown the light with no shock, to test "extinction retention". Skin conductivity was used to measure fear. There was a correlation between the thickness of the medial orbitofrontal cortex and lower skin conductivity.

Jack in "24" could be pretty thick.

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